RN-1747
Product Specifications
CAS Number
1024448-59-6
Target
TRP Channel
Applications
Neuronal Signaling
Smiles
[O-][N+] (=O) C1=C (C=CC (=C1) Cl) [S] (=O) (=O) N2CCN (CC2) CC3=CC=CC=C3
Molecular Formula
C17H18ClN3O4S
Additionnal Information
RN-1747 is a selective TRPV4 agonist with EC50s of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 also antagonizes TRPM8 with IC50 of 4 μM.
Storage Conditions
3 years -20°C powder
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