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Tertiapin-Q

Product Specifications

CAS Number

910044-56-3

Synonyms

TPNQ

Smiles

CCC (C) C1NC (=O) C (CCCNC (N) =N) NC (=O) C (CC (N) =O) NC (=O) C2CSSCC (NC (=O) C (CCCCN) NC (=O) C (CCCCN) NC (=O) C (CC3=C[NH]C4=CC=CC=C34) NC (=O) C (CSSCC (NC (=O) C (CC (C) C) NC (=O) C (C) N) C (=O) NC (CC (N) =O) C (=O) N2) NC (=O) C (CCC (N) =O) NC (=O) C (CC5=C[NH]C=N5) NC (=O) C6CCCN6C (=O) C (NC (=O) C (NC1=O) C (C) CC) C (C) CC) C (=O) NCC (=O) NC (CCCCN) C (=O) NC (CCCCN) C (N) =O

Molecular Formula

C106H175N35O24S4

Additionnal Information

Tertiapin-Q (TPNQ) is a derivative of tertiapin and inhibits BK-type K+ channels in a use- and concentration-dependent manner. Tertiapin-Q also binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with Ki values of 1.3 nM and 13.3 nM respectively.

Storage Conditions

3 years -20°C powder

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