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Glembatumumab vedotin

Product Specifications

CAS Number

1182215-65-1

Synonyms

CDX-011 (DOX), CR011, CR011-vcMMAE

Target

Others

Applications

Others

Additionnal Information

Glembatumumab vedotin (CDX-011 (DOX), CR011, CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of an fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma.

Storage Conditions

Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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