Glembatumumab vedotin
Product Specifications
CAS Number
1182215-65-1
Synonyms
CDX-011 (DOX), CR011, CR011-vcMMAE
Target
Others
Applications
Others
Additionnal Information
Glembatumumab vedotin (CDX-011 (DOX), CR011, CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of an fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma.
Storage Conditions
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
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