Tisotumab vedotin
Product Specifications
CAS Number
1418731-10-8
Specifications
4.2
Synonyms
TF-011-MMAE, HuMax-TF-ADC
Target
CD markers
Applications
Transmembrane Transporters
Additionnal Information
Tisotumab vedotin (TF-011-MMAE, HuMax-TF-ADC) is an antibody-drug conjugate (ADC) composed of a fully human monoclonal antibody to tissue factor III (thromboplastin) also known as CD142, conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinylp-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Tisotumab vedotin has the potential for use in research of solid tumors mainly in cervical cancer.
Storage Conditions
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
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