Disitamab vedotin
Product Specifications
CAS Number
2136633-23-1
Specifications
3.8
Synonyms
RC-48, RC 480-ADC
Target
EGFR
Applications
Protein Tyrosine Kinase
Additionnal Information
Disitamab Vedotin (RC-48 , RC 480-ADC) is an antibody-drug conjugate (ADC) composed of anti-[ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340) ] humanized monoclonal antibody, conjugated to monomethylauristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Disitamab Vedotin has the potential for use in solid tumors mainly in advanced breast cancer.
Storage Conditions
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
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