Depatuxizumab mafodotin
Product Specifications
CAS Number
1585973-65-4
Synonyms
ABT-414, Depatux-M
Target
EGFR
Applications
Protein Tyrosine Kinase
Additionnal Information
Depatuxizumab Mafodotin (Depatux-M, ABT-414) is an antibody-drug conjugate consisting of an EGFR IGg1 monoclonal antibody conjugated to the tubulin inhibitor monomethyl auristatin F via a stable maleimidocaproyl link. Depatuxizumab Mafodotin is used in the treatment of recurrent EGFR-amplified Glioblastoma (GBM) .
Storage Conditions
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
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