Ulocuplumab (Anti-CXCR4 / CD184)
Product Specifications
CAS Number
1375830-34-4
Synonyms
BMS 936564; MDX 1338; Anti-Human CXCR4 Recombinant Antibody
Target
CXCR
Applications
GPCR & G Protein
Additionnal Information
Ulocuplumab (Anti-CXCR4 / CD184) is a fully human IgG4 antibody, targeting CXCR4. Ulocuplumab induces apoptosis and inhibits CXCL12 mediated CXCR4 activation-migration of chronic lymphocytic leukemia (CLL) . Ulocuplumab exhibits antitumor activity in established tumors including acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL), and multiple myeloma xenograft models. MW: 144.84 KD.
Storage Conditions
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
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