Veledimex
Veledimex (INXN-1001), a synthetic analog of the insect molting hormone ecdysone, is an orally active activator ligand for a proprietary gene therapy promoter system. Veledimex can be used to activate certain genes using the ecdysone receptor (EcR) -based inducible gene regulation system, the RheoSwitch Therapeutic System (RTS) . Veledimex can cross blood-brain barrier (BBB) in both orthotopic GL-261 mice and cynomolgus monkeys[1][2].
Product Specifications
CAS Number
1093130-72-3
Product Name Alternative
INXN-1001; RG-115932
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Veledimex.html
Purity
98.77
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(NN(C(C1=CC(C)=CC(C)=C1)=O)[C@@H](C(C)(C)C)CCC)C2=CC=CC(OC)=C2CC
Molecular Formula
C27H38N2O3
Molecular Weight
438.60
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
IL-1; IL-12
Available Sizes
Frequently Asked Questions
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