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Elezanumab (Anti-RGMA)

Product Specifications

CAS Number

1791416-49-3

Synonyms

ABT-555, AE12-1Y-QL

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Additionnal Information

Elezanumab (Anti-RGMA) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa) . Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway with IC50 of 97 pM. MW: 146.44 kD.

Storage Conditions

Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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