Anti-mouse CD40L (CD154) -InVivo
Product Specifications
Specifications
Activated mouse Th1 clone D1.6
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Additionnal Information
The MR-1 monoclonal antibody reacts with mouse CD154 also known as CD40 ligand. The MR-1 monoclonal antibody has been reported to inhibit in vitro activation of B lymphocytes by blocking the binding of CD154 with CD40 on T helper cells as well as inhibit the formation of germinal centers and disrupt antigen-specific T cell responses. Additionally, the MR-1 antibody blocks interactions of T cells and antigen-presenting cells in vitro and blocks the development of experimental autoimmune disease in vivo.
Storage Conditions
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
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