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Denosumab (anti-RANK ligand)

Product Specifications

CAS Number

615258-40-7

Synonyms

AMG-162

Target

NF-κB

Applications

NF-κB

Additionnal Information

Denosumab (anti-RANK ligand) (AMG-162) is a fully human monoclonal antibody that selectively inhibits primate RANKL. Denosumab inhibits the ability of human RANKL (143–317) to stimulate the formation of osteoclasts derived from murine RAW 264.7 cells with an IC50 value of 1.64 nM.

Storage Conditions

Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

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