APC Anti-Rat CD172a Antibody[OX-41]
Product Specifications
Background
Rat CD172a, also known as a signal-regulatory protein (SIRP), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs) . The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a.
Abbreviation
CD172a
Synonyms
SIRPa; PTPNS1; BIT; MFR; p84; CD172 antigen-like family member A
Gene ID
19261
UniProt
P97710
Reactivity
Rat
Clonality
Monoclonal
Clone
OX-41
Conjugation
APC
Applications
FCM
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
Host or Source
Mouse
Recommended Usage
The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood) .
Control Catalog Number
E-AB-F09802E
Isotype
Mouse IgG2a, κ
Available Sizes
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