Purified Anti-Human CD335 Antibody[9E2]
Product Specifications
Background
CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+ NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.
Abbreviation
CD335
Synonyms
NKP; Activating NK receptor NK p46; FLJ99094; Lymphocyte antigen 94; Lymphocyte antigen 94 homolog (activating NK receptor; NCT1; NCTR1; NK cell activating receptor; NK p46) ; NCR; NK-p; Natural cytotoxicity triggering receptor; hNKp; CD335; LY94; NK-p46; NKP46; NCR1; hNKp46; Lymphocyte antigen 94 homolog; Natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; NK cell-activating receptor; NCR1
UniProt
O76036
Reactivity
Human
Immunogen
Recombinant Human CD335 protein
Clonality
Monoclonal
Clone
9E2
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Signal Transduction; CDs
Purification Method
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Host or Source
Mouse
Control Catalog Number
E-AB-F09793A
Isotype
Mouse IgG1, κ
Available Sizes
Frequently Asked Questions
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