Purified Anti-Human CD335 Antibody[9E2], Functional Grade
Product Specifications
Background
CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+ NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells. None (Azide-Free, Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Abbreviation
CD335
Synonyms
NKP; Activating NK receptor NK p46; FLJ99094; Lymphocyte antigen 94; Lymphocyte antigen 94 homolog (activating NK receptor; NCT1; NCTR1; NK cell activating receptor; NK p46) ; NCR; NK-p; Natural cytotoxicity triggering receptor; hNKp; CD335; LY94; NK-p46; NKP46; NCR1; hNKp46; Lymphocyte antigen 94 homolog; Natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; NK cell-activating receptor; NCR1
UniProt
O76036
Reactivity
Human
Immunogen
Recombinant Human CD335 protein
Clonality
Monoclonal
Clone
9E2
Conjugation
None (AF/LE)
Applications
FCM; FA
Purification Method
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Host or Source
Mouse
Control Catalog Number
E-AB-F097930
Isotype
Mouse IgG1, κ
Available Sizes
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