Purified Anti-Human CD226 Antibody[11A8]

DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells, monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a member of the immunoglobulin (Ig) -superfamily containing 2 Ig-like domains of the V-set. The ligands for CD226 are the poliovirus receptor (CD155) and its family member nectin-2 (CD112), which are broadly expressed on epithelial, endothelial and neuronal cells. CD226 is physically associated with LFA-1 in NK cells and activated T cells, and involved in LFA-1-mediated signaling.

PTA; DNAX accessory molecule; platelet and T cell activation antigen; TLiSA; PTA1; adhesion glycoprotein; CD226 antigen; CD226 molecule; DNAM 1; DNAM-1; DNAX accessory molecule 1; platelet and T cell activation antigen 1; T lineage specific activation antigen 1 antigen; TLiSA1; DNAM1; CD226; PTA-1; TLiSA1