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Purified Anti-Mouse CD200 Antibody[OX-90], Functional Grade

Product Specifications

Background

CD200, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily (1, 2) . The human CD200 cDNA encodes a 278 amino acid (aa) precursor that includes a 30 aa signal sequence, a 202 aa extracellular domain (ECD), a 27 aa transmembrane segment, and a 19 aa cytoplasmic domain. Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues (By similarity) . None (Azide-Free, Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.

Abbreviation

CD200

Synonyms

Mox; OX2; Mox2; MRC; OX-2; OX-2 membrane glycoprotein; Cd200

UniProt

O54901

Reactivity

Mouse

Immunogen

Recombinant Mouse CD200 protein

Clonality

Monoclonal

Clone

OX-90

Conjugation

None (AF/LE)

Applications

FCM; Block

Purification Method

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Host or Source

Rat

Control Catalog Number

E-AB-F098330

Isotype

Rat IgG2a, κ

Available Sizes

Frequently Asked Questions

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