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APC/Cyanine 7 Anti-Mouse CD45 Antibody[30-F11]

Selected Variant

E-AB-F1136N-01

Size: 50 Tests

Product Specifications

Background

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Abbreviation

CD45

Synonyms

Receptor-type tyrosine-protein phosphatase C; Ptprc; L-CA; Ly-5; T200; CD45

Gene ID

19264

UniProt

P06800

Reactivity

Mouse

Clonality

Monoclonal

Clone

30-F11

Conjugation

APC/Cyanine 7

Applications

FCM

Concentration

5 μL/Test

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.

Citation 01

https://link.springer.com/article/10.1186/s13046-025-03324-8

Citation 02

https://www.sciencedirect.com/science/article/pii/S0944711325012401

Citation 03

https://pubs.acs.org/doi/abs/10.1021/acsami.5c17578

Citation 04

https://www.mdpi.com/2310-2861/12/3/257

Citation 05

https://link.springer.com/article/10.1007/s00262-025-03949-w

Host or Source

Rat

Recommended Usage

The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood) .

Control Catalog Number

E-AB-F09842N

Isotype

Rat IgG2b, κ

Available Sizes

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