Recombinant BMP2 Monoclonal Antibody
Product Specifications
Background
Bone morphogenetic protein-2 (BMP-2) is a menmber of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer, 2 monomersthen associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-teminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TCF beta signaling pathway and cytokine-cytokine receptorinteraction.
Abbreviation
BMP2
Synonyms
BDA; BMP; BDA2; BMP2A; BMP2; BDA2A; BMP-2; BMP-2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A; Bmp-2; Bmp2; BDA; BDA2; BMP2A; BMP-2A; Bmp-2; Bmp2
UniProt
P12643; P21274; P49001
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant protein corresponding to Mouse BMP2
Clone
A0362R
Conjugation
Unconjugated
Applications
IHC; WB; IF; ELISA
Field of Research
Signal Transduction; Stem Cells; Cancer; Cardiovascular
Purification Method
Protein A purified
Concentration
1 mg/mL
Dilution
IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:2000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
45, 13 kDa
Observed Molecular Weight
30, 13 kDa
Host or Source
Rabbit
Isotype
IgG, κ
Available Sizes
Frequently Asked Questions
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