Purified Anti-Human NANOG Antibody[23D2-3C6]
Selected Variant
AN010430P-01
Size: 25 µg
Product Specifications
Background
Nanog is a transcription factor that plays key roles in the maintenance of pluripotency and self-renewal in embryonic stem cells. Nanog expression is regulated by other transcription factors, which include Sox2 and Oct-4. It also plays a role in epithelial malignancy and is enriched in cancer stem cells. The ablation of nanog is sufficient to reduce the cancer stem cell pool.
Abbreviation
NANOG
Synonyms
NANOG; Embryonic stem cell specific homeobox protein; ENK; FLJ12581; hNanog; Homeobox protein NANOG
UniProt
Q9H9S0
Reactivity
Human
Immunogen
Recombinant Human NANOG protein
Clonality
Monoclonal
Clone
23D2-3C6
Conjugation
Unconjugated
Applications
FCM
Field of Research
Stem Cells; Epigenetics and Nuclear Signaling; Developmental Biology; Cancer; Pluripotency Maintenance and Differentiation
Purification Method
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Host or Source
Mouse
Control Catalog Number
E-AB-F09793A
Isotype
Mouse IgG1, κ
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