Purified Anti-Human CX3CR1 Antibody[2A9-1]

CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also called GPR13 or V28. It is expressed on NK cells, T cell subset, monocytes/macrophages, dendritic cells, and some malignant epithelial cells. CX3CL1 (known also as fractalkine and neurotactin) is the ligand of CX3CR1. CX3CL1 is a unique transmembrane molecule with a CX3C-motif chemokine domain and a mucin-like stalk. CX3CL1 is expressed by activated-endothelial cells, neurons, and astrocytes. The interaction of CX3CR1 and its ligand mediatesfirm cell adhesion and migration.

Beta chemokine receptor-like 1; CMK-BRL1; CMK-BRL-1; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; fractalkine receptor; G-protein coupled receptor 13; GPR; CCRL; GPRV; CX3CR; CMKDR; CMKBRL; CX3CR1; CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28