Purified Anti-Human CD131 Antibody[BION-1]

CD131, also known as the IL-3R common β subunit (βC), is a 95-120 kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common β subunit associates with the specific α subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response.

/granulocyte-macrophage colony-stimulating factor receptor; beta; beta (high affinity) ; Beta-C; CDw131; Colony stimulating factor 2 receptor beta; Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage) ; Common beta chain; Cytokine receptor common beta chain; Cytokine receptor common beta chain precursor (CDw131 antigen) ; Cytokine receptor common subunit beta; GM CSF/IL 3/IL 5 receptor common beta chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; Interleukin 3 receptor; Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta (high affinity) ; Interleukin 5 receptor; SMDP5; stimulating factor 3 receptor; CD131; IL3RB; IL5RB; CSF2RB; common &beta- chain-n; CDw131; IL-3R&beta