PE Anti-Mouse CX3CR1 Antibody[SA011F11]
Product Specifications
Background
CX3CR1 is a 40 kD, G-protein coupled receptor, with seven transmembrane regions. CX3CR1 is expressed by resident and alternatively activated macrophages (M2), a subset of monocytes, dendritic cells (DCs), NK cells, a subset of memory T cells, and mast cells. CX3CR1 is involved in cell recruitment during inflammation and participates in cell adhesion and extravasation from blood vessels. Its ligand is CX3CL1, also known as fractalkine or neurotactin. CX3CR1 is also a coreceptor for HIV1 and variations in this gene leads to increased susceptibility to HIV. In the brain, it is expressed by glial cells, which interact with CX3CL1 expressed by neurons.
Abbreviation
CX3CR1
Synonyms
Chemokine (C-X3-C motif) receptor 1; Fractalkine receptor; GPR13; CCRL1; CMKBRL1; CMKDR1; V28
Gene ID
13051
UniProt
Q9Z0D9
Reactivity
Mouse
Clonality
Monoclonal
Clone
SA011F11
Conjugation
PE
Applications
FCM
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
Host or Source
Mouse
Recommended Usage
The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood) .
Control Catalog Number
E-AB-F09802D
Isotype
Mouse IgG2a, κ
Available Sizes
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