Purified Anti-Human CD159a Antibody[S19004C]

CD159a, also known as NKG2A or KLRC1, is a type II transmembrane protein. It belongs to the killer cell lectin-like receptor family also known as the NKG2 family. It is expressed on NK and NKT cells and T cell subsets. NKG2A is an inhibitory NK cell receptor and it is expressed as a heterodimer with CD94. In human, NKG2A/CD94 complex interacts HLA-E on target cells and inhibits T cells and NK cell effector functions. Recent studies showed that NKG2A blockade enhances the anti-tumor effect of NK cell and CD8+ T cells.

NKG; C lectin type II protein; CD159 antigen like family member A; CD159a antigen; Killer cell lectin like receptor subfamily C member 1; MGC13374; MGC59791; Natural killer cell lectin; Natural killer cell protein group 2-A1; Natural killer cell receptor NKG2A; Natural killer group protein 2; NKG2 1/B activating NK receptor; NKG2 A; NKG2 A/B activating NK receptor; NKG2 A/B type II integral membrane protein; NKG2 A/NKG2 B type II integral membrane protein; NKG2 B; NKG2-1/B activating NK receptor; NKG2A; NKG2B; rNKG2A; KLRC; KLRC1; CD159A; NKG2; NKG2A; CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein