Purified Anti-Whitlow 218 Linker Antibody[DA011]
Selected Variant
AN009990P-01
Size: 25 µg
Product Specifications
Background
The whitlow/218 linker, with the sequence GSTSGSGKPGSGEGSTKG, is a commonly used synthetic peptide linker. Whitlow/218 linker often leveraged to connect the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The scFv containing the 218 linker showed reduced aggregation and was found to be more stable to proteolysis in vitro.
Abbreviation
Whitlow 218 Linker
Immunogen
Synthetic peptide
Clonality
Monoclonal
Clone
DA011
Conjugation
Unconjugated
Applications
FCM
Purification Method
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
Rabbit IgG
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