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Purified Anti-Human CD14 Antibody[HCD14]

Product Specifications

Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

Abbreviation

CD14

Synonyms

CD14; CD_antigen=CD14; LPS-R; membrane-bound form; Mo2; Monocyte differentiation antigen CD14 urinary form; Myeloid cell specific leucine rich glycoprotein; monocyte differentiation antigen CD; CD14; soluble; CD14 antigen; CD14 molecule; monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; LPS R

UniProt

P08571

Reactivity

Human

Immunogen

Recombinant Human CD14 protein

Clonality

Monoclonal

Clone

HCD14

Conjugation

Unconjugated

Applications

FCM

Field of Research

Lysates; Stem Cells; Kits; Immunology; Other; CDs; Toll-like Receptor Signaling Pathway; TLR Signaling; Endothelial Progenitors Markers; Hematopoietic Stem Cell Markers; Mesenchymal Stem Cells

Purification Method

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Host or Source

Mouse

Control Catalog Number

E-AB-F09793A

Isotype

Mouse IgG1, κ

Available Sizes

Frequently Asked Questions

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