Purified Anti-Human CD14 Antibody[HCD14]
Product Specifications
Background
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.
Abbreviation
CD14
Synonyms
CD14; CD_antigen=CD14; LPS-R; membrane-bound form; Mo2; Monocyte differentiation antigen CD14 urinary form; Myeloid cell specific leucine rich glycoprotein; monocyte differentiation antigen CD; CD14; soluble; CD14 antigen; CD14 molecule; monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; LPS R
UniProt
P08571
Reactivity
Human
Immunogen
Recombinant Human CD14 protein
Clonality
Monoclonal
Clone
HCD14
Conjugation
Unconjugated
Applications
FCM
Field of Research
Lysates; Stem Cells; Kits; Immunology; Other; CDs; Toll-like Receptor Signaling Pathway; TLR Signaling; Endothelial Progenitors Markers; Hematopoietic Stem Cell Markers; Mesenchymal Stem Cells
Purification Method
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Host or Source
Mouse
Control Catalog Number
E-AB-F09793A
Isotype
Mouse IgG1, κ
Available Sizes
Frequently Asked Questions
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