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Purified Anti-Human CD40 Antibody[HB14]

Selected Variant

AN008840P-01

Size: 25 µg

Product Specifications

Background

CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The mature hCD40 consists of a 172 amino acid (aa) extracellular domain, a 22 aa transmembrane region and a 62 aa cytoplasmic domain . Human and mouse CD40 share 62% aa identity. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines.

Abbreviation

CD40

Synonyms

CDW; AI326936; B cell associated molecule CD40; B cell surface antigen CD40; B cell-associated molecule; CD 40; CD40 (protein) ; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5) ; CD40 molecule; CD40 protein; CD40 type II isoform; GP39; HIGM1; IGM; IMD3; isoform CRA_a; member 5; MGC9013; Nerve growth factor receptor related B lymphocyte activation molecule; OTTHUMP00000031699; OTTHUMP00000031700; TBAM; T-BAM; TNF receptor superfamily member 5; TNR5; TRAP; Tumor necrosis factor receptor superfamily; Tumor necrosis factor receptor superfamily member 5 precursor; B-cell surface antigen CD; Tumor necrosis factor receptor superfamily member; TNFRSF; CD40; Bp50; CDW40; TNFRSF5; p50; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; CD40L receptor; TNFRSF5

UniProt

P25942

Reactivity

Human

Immunogen

Recombinant Human CD40 protein

Clonality

Monoclonal

Clone

HB14

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology; Stem Cells; Cardiovascular Biology; CDs; B Cell Receptor Signaling Pathway; NF-kB Signaling Pathway; Hematopoietic Stem Cell Markers

Purification Method

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Host or Source

Mouse

Control Catalog Number

E-AB-F09793A

Isotype

Mouse IgG1, κ

Available Sizes

Price

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