Purified Anti-Human CD40 Antibody[HB14]
Selected Variant
AN008840P-01
Size: 25 µg
Product Specifications
Background
CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The mature hCD40 consists of a 172 amino acid (aa) extracellular domain, a 22 aa transmembrane region and a 62 aa cytoplasmic domain . Human and mouse CD40 share 62% aa identity. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines.
Abbreviation
CD40
Synonyms
CDW; AI326936; B cell associated molecule CD40; B cell surface antigen CD40; B cell-associated molecule; CD 40; CD40 (protein) ; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5) ; CD40 molecule; CD40 protein; CD40 type II isoform; GP39; HIGM1; IGM; IMD3; isoform CRA_a; member 5; MGC9013; Nerve growth factor receptor related B lymphocyte activation molecule; OTTHUMP00000031699; OTTHUMP00000031700; TBAM; T-BAM; TNF receptor superfamily member 5; TNR5; TRAP; Tumor necrosis factor receptor superfamily; Tumor necrosis factor receptor superfamily member 5 precursor; B-cell surface antigen CD; Tumor necrosis factor receptor superfamily member; TNFRSF; CD40; Bp50; CDW40; TNFRSF5; p50; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; CD40L receptor; TNFRSF5
UniProt
P25942
Reactivity
Human
Immunogen
Recombinant Human CD40 protein
Clonality
Monoclonal
Clone
HB14
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Stem Cells; Cardiovascular Biology; CDs; B Cell Receptor Signaling Pathway; NF-kB Signaling Pathway; Hematopoietic Stem Cell Markers
Purification Method
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Host or Source
Mouse
Control Catalog Number
E-AB-F09793A
Isotype
Mouse IgG1, κ
Available Sizes
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