Purified Anti-Human ROR1 Antibody[DA009]

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Inactive tyrosine protein kinase transmembrane receptor ROR1; MGC99659; Neurotrophic tyrosine kinase receptor related 1; OTTHUMP00000010573; OTTHUMP00000010574; OTTMUSP00000008344; receptor related 1; Receptor tyrosine kinase like orphan receptor 1; RGD1559469; ROR 1; RP11 24J23.1; Tyrosine kinase like orphan receptor 1; Tyrosine protein kinase transmembrane receptor ROR1; Tyrosine-protein kinase transmembrane receptor ROR1; ROR; receptor-related; Inactive tyrosine-protein kinase transmembrane receptor ROR; NTRKR; dJ537F; ROR1; NTRKR1; dJ537F10.1; Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase; receptor-related 1