Purified Anti-Human TNF-α Antibody[MAb11]

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Tumor Necrosis Factor Ligand Superfamily Member; TNFSF; TNF; DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F; TNF alpha; Cachectin; Tumor Necrosis Factor; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; APC1; APC1 protein; DIF; TNF-alpha; TNFA; TNFSF2; Differentiation inducing factor; Macrophage cytotoxic factor; macrophage derived; member 2; Membrane Form; monocyte derived; soluble form; sTNFA; TNF superfamily; Tumor necrosis factor alpha