PE Anti-Human IL-12/IL-23 p40 Antibody[C8.6]

The C8.6 antibody reacts with human IL-12 p40 subunit of the IL-12 p70 heterodimer and IL-23 p40 subunit of the IL-23 p19/p40, as well as p40 monomer and homodimer. The C8.6 antibody has been reported to strongly inhibit different biological activities of IL-12, (e.g., IFN-gamma induction, mitogenic effects on PHA blasts, and enhancement of NK cell-mediated cytotoxicity) . The C8.6 antibody can neutralize the bioactivity of natural or recombinant IL-12.

Interleukin-12 p40; Interleukin-23 p40; Cytotoxic lymphocyte maturation factor (CLMF) ; Natural killer cell stimulatory factor (NKSF) ; CTL maturation factor (TcMF) ; T-cell stimulating factor (TSF) ; AN008430