Purified Anti-Mouse TNF-α Antibody[TN3-19.12]

Tumor necrosis factor alpha (TNF-alpha, TNF- alpha, TNFA), also known as Cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism. TNF-alpha is produced by several lymphoid cells as well as by astrocytes, endothelial cells, and smooth muscle cells. Mouse TNF-alpha consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 179 aa extracellular domain (ECD) .

Tumor necrosis factor ligand superfamily member; TNFSF; DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha; ICD1; ICD2; Membrane Form; N-terminal fragment; NTF; Tnf; Cachectin; Tumor necrosis factor; Tumor necrosis factor ligand superfamily member 2; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; Tnlg1f; TNFSF2; TNF; TNFa