PE Anti-Human CD32 Antibody[MDE-8]
Product Specifications
Background
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform) .
Abbreviation
CD32
Synonyms
FCR II; FcγRII
Gene ID
2212
UniProt
P31995
Reactivity
Human
Clonality
Monoclonal
Clone
MDE-8
Conjugation
PE
Applications
FCM
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
Host or Source
Mouse
Recommended Usage
The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood) .
Control Catalog Number
E-AB-F09792D
Isotype
Mouse IgG1, κ
Available Sizes
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