Glutamine synthetase
Glutamine synthetase is an enzyme that converts glutamate and ammonia into glutamine. Glutamine synthetase can inhibit angiogenesis in ocular and inflammatory skin diseases. Glutamine synthetase can also palmitoylate RHOJ, thereby inhibiting endothelial cell migration. Glutamine synthetase can be used in research on various diseases, including cardiovascular and cerebrovascular diseases and cancer[1][2].
Product Specifications
CAS Number
[9023-70-5]
UNSPSC
12352204
Target
Biochemical Assay Reagents
Type
Enzyme
Related Pathways
Others
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/glutamine-synthetase.html
Solubility
10 mM in DMSO
Smiles
[Glutaminesynthetase]
References & Citations
[1]Eelen G, et al. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature. 2018 Sep;561 (7721) :63-69. |[2]Matés JM, et al. Dysregulation of glutaminase and glutamine synthetase in cancer. Cancer Lett. 2019 Dec 28;467:29-39.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
Curated Selection
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