Glutamine synthetase

Glutamine synthetase is an enzyme that converts glutamate and ammonia into glutamine. Glutamine synthetase can inhibit angiogenesis in ocular and inflammatory skin diseases. Glutamine synthetase can also palmitoylate RHOJ, thereby inhibiting endothelial cell migration. Glutamine synthetase can be used in research on various diseases, including cardiovascular and cerebrovascular diseases and cancer[1][2].

Product Specifications

CAS Number

[9023-70-5]

UNSPSC

12352204

Target

Biochemical Assay Reagents

Type

Enzyme

Related Pathways

Others

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/glutamine-synthetase.html

Solubility

10 mM in DMSO

Smiles

[Glutaminesynthetase]

References & Citations

[1]Eelen G, et al. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature. 2018 Sep;561 (7721) :63-69. |[2]Matés JM, et al. Dysregulation of glutaminase and glutamine synthetase in cancer. Cancer Lett. 2019 Dec 28;467:29-39.