HMGB-1 Polyclonal antibody

Product Specifications

Background

Human High-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 30 kDa, 215 amino acid (aa) single chain polypeptide containing three domains: two N-terminal globular, 70 aa positively charged DNA-binding domains (HMG boxes A and B), and a negatively charged 30 aa C-terminal region that contains only Asp and Glu . Residues 27‑43 and 178‑184 contain a NLS. Posttranslational modifications of the molecule have been reported, with acetylation occurring on as many as 17 lysine residues.

Abbreviation

HMGB-1

UniProt

P09429

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human HMGB-1 protein expressed by E.coli

Target

High mobility group protein 1; high mobility group protein B1; high-mobility group box 1; HMG1; HMG-1; HMG1DKFZp686A04236; HMG3; HMGB1; SBP-1; Chromosomal protein; DKFZp686A04236; High mobility group 1; High mobility group box 1; high-mobility group (nonhistone chromosomal) protein 1; HMGB 1; nonhistone; NONHISTONE CHROMOSOMAL PROTEIN HMG1; SBP 1; Sulfoglucuronyl carbohydrate binding protein; SBP; HMGB; High Mobility Group Protein; High mobility group protein B; HMG; HMG-1; HMG1; HMG3; SBP-1; HMGB1; Amphoterin; High Mobility Group Protein 1; High mobility group protein B1; High mobility group protein 1 (HMG-1)