MeSeI
MeSeI exhibits a weak inhibitory activity against monoamine oxidase MAO-A and MAO-B (IC50=198.8 µM) . MeSeI regulates dopamine receptor D2 and norepinephrine receptor α2, β1, and exhibits antidepressant-like effect in mice. MeSeI is orally active[1].
Product Specifications
CAS Number
2901664-87-5
UNSPSC
12352005
Target
Androgen Receptor; Dopamine Receptor; Monoamine Oxidase
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling; Vitamin D Related/Nuclear Receptor
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mesei.html
Smiles
CC1=CC=C(C2=CN3C=CC=CC3=C2[Se]C4=CC=CC=C4)C=C1
Molecular Formula
C21H17NSe
Molecular Weight
362.33
References & Citations
[1]da Rocha MJ, et al., 1- (Phenylselanyl) -2- (p-tolyl) indolizine: A selenoindolizine with potential antidepressant-like activity in mice mediated by the modulation of dopaminergic and noradrenergic systems. Brain Res. 2024 Jul 1;1834:148904.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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