CRS3123 (dihydrochloride)

CRS3123 (REP-3123) dihydrochloride, a fully synthetic antibacterial agent, potently inhibits methionyl-tRNA synthetase (MetRS) of Clostridioides difficile, inhibiting Clostridioides difficile toxin production and spore formation. CRS3123 dihydrochloride is an oral agent for the research of Clostridioides difficile infection (CDI) [1].

Product Specifications

CAS Number

[1013915-99-5]

Product Name Alternative

REP-3123 (dihydrochloride)

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/crs3123-dihydrochloride.html

Concentration

10mM

Purity

99.11

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C2=C(C=CS2)NC(NCCCN[C@@H]3CCOC4=C(Br)C=C(Br)C=C34)=C1.[H]Cl.[H]Cl

Molecular Formula

C19H21Br2Cl2N3O2S

Molecular Weight

586.17

References & Citations

[1]Agent with Minimal Disruption of Normal Gut Microbiota. Antimicrob Agents Chemother. 2019 Dec 20;64 (1) :e01395-19.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

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