Dehydroabietinol
Dehydroabietinol is an abietane diterpenoid. Dehydroabietinol has kinase inhibition activity for spleen tyrosine kinase (SYK) with an IC50 value of 46.4 μM. Dehydroabietinol can be used for the research of immune-mediated disease[1].
Product Specifications
CAS Number
3772-55-2
UNSPSC
12352005
Target
Syk
Type
Natural Products
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dehydroabietinol.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12C3=CC=C(C(C)C)C=C3CC[C@@]1([H])[C@@](C)(CCC2)CO
Molecular Formula
C20H30O
Molecular Weight
286.45
References & Citations
[1]Jun-Bo Gao, et al. Isolation, Characterization, and Structure-Activity Relationship Analysis of Abietane Diterpenoids from Callicarpa bodinieri as Spleen Tyrosine Kinase Inhibitors. J Nat Prod. 2018 Apr 27;81 (4) :998-1006.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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