Ac-LEHD-CHO
Product Specifications
UNSPSC Description
Ac-LEHD-CHO is an inhibitor for caspase 8/9. Ac-LEHD-CHO prevents GalN/TNF-α-induced hepatotoxicity and hepatocyte apoptosis[1].
Target Antigen
Apoptosis; Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-lehd-cho.html
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@H](NC(C)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C=O)CC(O)=O)=O)CC1=CN=CN1)=O)=O
Molecular Weight
538.55
References & Citations
[1]Kermer P, et al., Caspase-9: involvement in secondary death of axotomized rat retinal ganglion cells in vivo. Brain Res Mol Brain Res. 2000 Dec 28;85(1-2):144-50.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10241/Ac-LEHD-CHO-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10241/
Clinical Information
No Development Reported
CAS Number
319494-38-7
Curated Selection
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