Ac-LEHD-CHO
Ac-LEHD-CHO is an inhibitor for caspase 8/9. Ac-LEHD-CHO prevents GalN/TNF-α-induced hepatotoxicity and hepatocyte apoptosis[1].
Product Specifications
CAS Number
[319494-38-7]
UNSPSC
12352209
Target
Apoptosis; Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-lehd-cho.html
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@H](NC(C)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C=O)CC(O)=O)=O)CC1=CN=CN1)=O)=O
Molecular Formula
C23H34N6O9
Molecular Weight
538.55
References & Citations
[1]Kermer P, et al., Caspase-9: involvement in secondary death of axotomized rat retinal ganglion cells in vivo. Brain Res Mol Brain Res. 2000 Dec 28;85 (1-2) :144-50.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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