Naphthalene-2,3-Dicarboxaldehyde

Naphthalene-2,3-Dicarboxaldehyde (2,3-Naphthalenedicarboxaldehyde), a phthaldehyde derivative, is a fungal ASADH inhibitor (Ki: 45 μM) . Naphthalene-2,3-Dicarboxaldehyde inhibits the growth of C. albicans CAF2-1 with IC50 of 58.2 μM and MIC of 12 μg/mL[1].

Product Specifications

CAS Number

[7149-49-7]

Product Name Alternative

2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/naphthalene-2-3-dicarboxaldehyde.html

Purity

99.37

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=CC1=CC2=CC=CC=C2C=C1C=O

Molecular Formula

C12H8O2

Molecular Weight

184.19

Precautions

H315, H319, H335

References & Citations

[1]Dahal GP, et al. Aspartate semialdehyde dehydrogenase inhibition suppresses the growth of the pathogenic fungus Candida albicans. Drug Dev Res. 2020 Sep;81 (6) :736-744.