Schiarisanrin A
Schiarisanrin A (Kadsulignan J) is a lignan with inhibitory activity on NO production. Schiarisanrin A inhibits NO production in BV-2 cells with an IC50 of 9.6 μM[1].
Product Specifications
CAS Number
130252-41-4
Product Name Alternative
Kadsulignan J
UNSPSC
12352005
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/schiarisanrin-a.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@]23C4=C([C@@H]([C@@H]([C@@H](CC3=CC(OC)=C1OC)C)C)OC([C@@H](C)CC)=O)C=C(OCO5)C5=C4OC2
Molecular Formula
C27H32O8
Molecular Weight
484.54
References & Citations
[1]Fang L, et al. Lignans from the roots of Kadsura coccinea and their inhibitory activities on LPS-induced NO production[J]. Phytochemistry Letters, 2014, 9: 158-162.|[2]Fang L. et al. Lignans from the roots of Kadsura coccinea and their inhibitory activities on LPS-induced NO production[J]. Phytochemistry Letters, 2014, 9: 158-162.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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