Minoxidil sulfate

Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo[1][3].

Product Specifications

CAS Number

[83701-22-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/minoxidil-sulfate.html

Purity

98.00

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=NC(N2CCCCC2)=CC(N1OS(=O)(O)=O)=N

Molecular Formula

C9H15N5O4S

Molecular Weight

289.31

Precautions

H302, H315, H319, H335

References & Citations

[1]A E Buhl, et al. Minoxidil sulfate is the active metabolite that stimulates hair follicles. J Invest Dermatol. 1990 Nov;95 (5) :553-7.|[2]Yan-ting Gu, et al. Minoxidil sulfate induced the increase in blood-brain tumor barrier permeability through ROS/RhoA/PI3K/PKB signaling pathway.Neuropharmacology 2013 Dec;75:407-15.doi: 10.1016/j.neuropharm.|[3]Y Nakaya, et al.Effect of minoxidil sulfate and pinacidil on single potassium channel current in cultured human outer root sheath cells and dermal papilla cells. J Dermatol Sci. 1994 Jul;7 Suppl:S104-8.