4'-Methoxychalcone

4'-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. 4'-Methoxychalcone modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity[1].

Product Specifications

CAS Number

[959-23-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PARP

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/4-methoxychalcone.html

Purity

99.82

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(OC)C=C1)/C=C/C2=CC=CC=C2

Molecular Formula

C16H14O2

Molecular Weight

238.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Han Y, et al. Regulatory effects of 4-methoxychalcone on adipocyte differentiation through PPARγ activation and reverse effect on TNF-α in 3T3-L1 cells. Food Chem Toxicol. 2017 Aug;106 (Pt A) :17-24.