3CAI
3CAI is a potent and specific AKT1 and AKT2 inhibitor.
Product Specifications
CAS Number
[28755-03-5]
UNSPSC
12352005
Hazard Statement
H302, H319
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3cai.html
Purity
98.32
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(CCl)C1=CNC2=CC=CC=C12
Molecular Formula
C10H8ClNO
Molecular Weight
193.63
Precautions
H302, H319
References & Citations
[1]Kim DJ, et al. (3-Chloroacetyl) -indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo. Cancer Prev Res (Phila) . 2011 Nov;4 (11) :1842-51.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Akt1; Akt2
Available Sizes
Curated Selection
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