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3CAI

3CAI is a potent and specific AKT1 and AKT2 inhibitor.

Product Specifications

CAS Number

28755-03-5

UNSPSC

12352005

Hazard Statement

H302, H319

Target

Akt

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3cai.html

Purity

98.32

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(CCl)C1=CNC2=CC=CC=C12

Molecular Formula

C10H8ClNO

Molecular Weight

193.63

Precautions

H302, H319

References & Citations

[1]Kim DJ, et al. (3-Chloroacetyl) -indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo. Cancer Prev Res (Phila) . 2011 Nov;4 (11) :1842-51.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Akt1; Akt2

Available Sizes

Frequently Asked Questions

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