MMP-9/MMP-13 Inhibitor I
MMP-9/MMP-13 Inhibitor I is a potent MMP-9 and MMP-13 inhibitor with IC50s of both 0.9 nM. MMP-9/MMP-13 Inhibitor I shows >20-folds selectivity for MMP-9/MMP-13 over other MMPs[1].
Product Specifications
CAS Number
[204140-01-2]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mmp-9-mmp-13-inhibitor-i.html
Purity
99.68
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1N(S(=O)(C2=CC=C(OC)C=C2)=O)CCN(C(C3=CC=C(C4=CC=CC=C4)C=C3)=O)C1)NO
Molecular Formula
C25H25N3O6S
Molecular Weight
495.55
Precautions
H315, H319, H335
References & Citations
[1]M Cheng, et al. Design and synthesis of piperazine-based matrix metalloproteinase inhibitors. J Med Chem. 2000 Feb 10;43 (3) :369-80.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-1; MMP-13; MMP-3; MMP-7; MMP-9
Available Sizes
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