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IRF-7 (phospho-Ser471/472) rabbit pAb

IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008],

Product Specifications

Background

IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008]

Synonyms

Interferon regulatory factor 7 (IRF-7)

Gene ID

3665

UniProt

Q92985

Cellular Locus

Nucleus. Cytoplasm. The phosphorylated and active form accumulates selectively in the nucleus.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized phosho peptide around human IRF-7 (Ser471 and 472)

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300

Molecular Weight

55kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES15429-1.pdf

Observed Molecular Weight

55 kD

Subcellular Location

Nucleus. Cytoplasm. The phosphorylated and active form accumulates selectively in the nucleus.

Other Product Names

Interferon regulatory factor 7 (IRF-7)

Gene ID (Human)

3665

SwissProt (Human)

Q92985

Available Sizes

Curated Selection

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