Opevesostat

Opevesostat (MK-5684; ODM-208) is an orally active and selective CYP11A1 inhibitor. Opevesostat has the potential for the research of metastatic castration-resistant prostate cancer (mCRPC) [1].

Product Specifications

CAS Number

[2231294-96-3]

Product Name Alternative

MK-5684; ODM-208

UNSPSC

12352005

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/opevesostat.html

Purity

99.79

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1C=C(CN2CC3=C(C2)C=CC=C3)OC=C1OCC4CCN(S(=O)(C)=O)CC4

Molecular Formula

C21H26N2O5S

Molecular Weight

418.51

References & Citations

[1]Fizazi, K. et al. 1605P Opevesostat (MK-5684/ODM-208), an oral CYP11A1 inhibitor, in metastatic castration-resistant prostate cancer (mCRPC) : Updated CYPIDES phase II results. Annals of Oncology, Volume 35, S968.