3-Methyl-L-histidine-d3

3-Methyl-L-histidine-d3 is the deuterium labeled 3-Methyl-L-histidine. 3-Methyl-L-histidine is an endogenous amino acid that can be found in actin and myosin[1].

Product Specifications

CAS Number

[144868-18-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Purity

99.0

Solubility

10 mM in DMSO

Smiles

OC([C@@H](N)CC1=CN=CN1C([2H])([2H])[2H])=O

Molecular Formula

C7H8D3N3O2

Molecular Weight

172.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]White WJ, Lawrie RA. Variations in the levels of 3-methyl-l-histidine of the myosins within the bovine carcass. Meat Sci. 1985;15 (3) :173-81. |[3]Zhu S, et al. Microbiota-derived 3-Methyl-L-histidine mediates the proatherogenic effect of high chicken protein diet. MedComm (2020) . 2025 Feb 13;6 (2) :e70090.