(Rac) -AF710B

(Rac) -AF710B is the racemate of AF710B (HY-116586) . AF710B is a highly potent and selective allosteric M1 muscarinic and σ1 receptor agonist. AF710B can be used for the research of Alzheimer’s disease[1].

Product Specifications

CAS Number

[1235733-73-9]

UNSPSC

12352005

Target

MAChR; Sigma Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-af710b.html

Smiles

O=C(CCC1=CNC2=C1C=CC=C2)N3CC4(CCN(CC4)C)SC3C

Molecular Formula

C20H27N3OS

Molecular Weight

357.51

References & Citations

[1]Fisher A, et al. AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer’s Disease. Neurodegener Dis. 2016;16 (1-2) :95-110.