Diprotin B
Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue[1][2].
Product Specifications
CAS Number
90614-49-6
UNSPSC
12352209
Hazard Statement
H302
Target
Dipeptidyl Peptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/diprotin-b.html
Purity
99.60
Solubility
H2O : ≥ 100 mg/mL
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H]1N(C([C@H](C(C)C)N)=O)CCC1)=O
Molecular Formula
C16H29N3O4
Molecular Weight
327.42
Precautions
H302
References & Citations
[1]Rahfeld J, et al. Are diprotin A (Ile-Pro-Ile) and diprotin B (Val-Pro-Leu) inhibitors or substrates of dipeptidyl peptidase IV? Biochim Biophys Acta. 1991 Jan 29;1076 (2) :314-6.|[2]Hatanaka T, et al. Inhibitory effect of collagen-derived tripeptides on dipeptidylpeptidase-IV activity. J Enzyme Inhib Med Chem. 2014 Dec;29 (6) :823-8.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
